I've tried Chrome, but I don't get the hype.
It crashes frequently to the point of absurdity.
It has dumb glitches like not being able to ever turn off Google Instant.
It has next to zero customization for things that matter like toolbar placement (oh wait, you don't get any toolbar options!), tabs, and whatnot.
It has bare-bones options, as in options-options
It lacks an about:config for increased customization and optimization like firefox.
It reloads pages so that if you have several tabs open and go back to one it will have to load again, even though it already did it the first time.
It cannot handle having many tabs like firefox can, and typically crashes when you do.
It just doesn't feel secure as far as browsers go, especially since Google searches have become hit and miss (especially google images, where a random and completely innocent image can be a virus).
It always seems to crash when I try to use a session manager with more than a couple tabs because the damn thing tries to load every tab at once instead of one - finish - then the next - finish - ect., something firefox does.
And it doesn't even have a tab scroll if you have a lot of tabs; it just shrinks the individual tabs until you can't tell what they are.
Don't get me wrong, I use it alongside firefox and opera and I certainly prefer it over IE, but it just has so many damn flaws that I wish they'd work on. The lack of user control really makes Chrome irksome for me and has become the unusually common reason why I wind up cursing at my computer.