I could go all day, so I'll limit myself to one per category.
Comics:
'The detective is correct. This is not the way I do business. I need people to have faith in me, gentlemen. Faith that I'll reward those who serve me well... and punish those who do not.' -Mr. Negative, Spider Man
Movies:
'Would you like to see my mask? I use it in my experiments. Probably not too frightening, to a tough guy, like you, but these crazies... they can't stand it. They SCREAM and they CRY. Much as you are doing now.' -Dr. Jonathan Crane, Batman Begins
Animation:
[While the valley he's in is on fire and Dinobot has just said his name]
'Hmmm, my ears are burning! Yesssssss! Why, Dinobot! What a delightful surprise. Erm, where are we now? Oh yes. I have the golden disk. I have the power to control the future. And the only remaining obstacle in my path to unimaginable glory... is yourself. Exhausted. Damaged beyond recovery. DEFEATED.' -Megatron, Beast Wars
Video Games:
'You think yourself above the will of God? Deplorable... this is truly deplorable, Nikanoru. Death is only a start. There will be songs written about the beauty of the pain I will inflict upon you all!' -Deathevans, Breath of Fire 2
Comics:
'The detective is correct. This is not the way I do business. I need people to have faith in me, gentlemen. Faith that I'll reward those who serve me well... and punish those who do not.' -Mr. Negative, Spider Man
Movies:
'Would you like to see my mask? I use it in my experiments. Probably not too frightening, to a tough guy, like you, but these crazies... they can't stand it. They SCREAM and they CRY. Much as you are doing now.' -Dr. Jonathan Crane, Batman Begins
Animation:
[While the valley he's in is on fire and Dinobot has just said his name]
'Hmmm, my ears are burning! Yesssssss! Why, Dinobot! What a delightful surprise. Erm, where are we now? Oh yes. I have the golden disk. I have the power to control the future. And the only remaining obstacle in my path to unimaginable glory... is yourself. Exhausted. Damaged beyond recovery. DEFEATED.' -Megatron, Beast Wars
Video Games:
'You think yourself above the will of God? Deplorable... this is truly deplorable, Nikanoru. Death is only a start. There will be songs written about the beauty of the pain I will inflict upon you all!' -Deathevans, Breath of Fire 2