Borderlands has me pretty pissed off right now.
For the Secret Armory of General Knoxx DLC, after you defeat Knoxx, you blow up the armory, right? So you walk in, and you're standing on an elevator. There are three buttons to press. You are not told which button to press.
I press the left-most button. The bomb becomes active. I press the middle button. The elevator takes me down into the armory.
Oh, that one on the right? Yeah, that's the one that actually ends the quest, and if you don't press it before lowering the elevator, you're screwed and can never complete that quest or the two subsequent quests breaking back into the armory.
Apparently the only way to get around it is to find someone online who just happens to be at the end of the Knoxx quest and piggyback your way into the armory.
But, for the most part, I don't get angry at games. For instance, I recently played Deus Ex (the original) for the first time, and I really didn't like the gameplay. So I just turned God mode on. *shrug* I was only there for the story, anyway.