Milla's secret chamber is one of the best, but my favorite is from Silent hill 2, really close to the end, when the staircase is in flames. Angela starts walking up the staircase, and James says "It's hot as hell in here." she stops, looks back, and says, "You see it too. For me, it's always like this." and then turns around and slowly walks into the fire. Not only is it incredibly freaky and creepy and depressing and tragic, the music is perfect for it. Way more disturbing than the rape scene, at least for me. You can watch it here, but it has a way bigger impact when you see it the first time you play the game. http://www.youtube.com/watch?v=cvnoMPode6E