I'm a political moderate. This means, at some point, everyone pisses me off when they start talking politics. In fact, replacing an interesting philosophical discussion on how Egyptians viewed mortality with some bullshit environmentalist agenda that's not going to matter some years down the line in the Watchmen film gives me great cause to want to chop off heads.
However, letting it bother me would just keep me from reading, watching or playing a lot of interesting pieces of entertainment. Besides, reading a book by someone that disagrees with you could potentially educate you and help you see how ignorant of something you really are. It helps me all the time. Ultimately, it is pretty foolish to let someone's political position effect your perception of a piece of entertainment. You are supporting the work the man put forward writing the game, not what he put forth politically.
That said, if the game were to have a bunch of anti-gay propoganda, there would be legitimate cause for concern. If it does not, then there is no problem.