Woodsey said:
"There seems to some subtext there that no one is saying, namely that the inclusion of actual homosexual relationships might hurt sales,"
But:
a) They had no problems with that with Dragon Age
b) Really? Couldn't you then say that about there being a black character (let's face it, racism and homophobia generally seem to go in hand)?
Dragon Age and Mass Effect are too very different games though. The Dragon Age protagonist is easily moulded and lacks a lot of depth to continue a story based on them, while Commander Shepard is a character that works around a manly or butch sense and as Bioware are the creators, they want to keep their depiction of Shepard intact.
Does it really matter anyway? Not every game needs a romantic sub-plot and even if it does contain one, it does not have to support every sexual preference. What if I had a fetish for dragons rooting cars? I might protest against ME3 until my Shepard can be a hermaphrodite dragon which is able to develop a relationship with homosexual cars.