A Weakgeek said:
I dont understand what it means to feel like you were born the wrong gender. There isn't a way males or females are supposed to think. According to societys standards there might be, but not in reality, so how could you "be the other gender in your mind or thoughts". I mean, your thoughts may fit in with the opposite genders stereotypical way of thinking, but thats not the same thing.
It's difficult to explain gender dysphoria to someone who hasn't experienced it, it'd be like explaining pain to someone who hasn't experienced it, you really do need to feel it to understand. But I'll try.
Our brains are set to a gender (this can be anything from the conventional male and female, to both genders, gender fluid, androgynous, etc.), and in most people, the gender our brain is set to matches the sex characteristics you have been provided with. These people (the correct term is cispeople) generally don't appreciate or understand the difference between gender and sex without education about it, because they can't distinguish between them, since they match up inside them. In transpeople, the gender the brain is set to does not match the sex characteristics provided, causing the dysphoria.
Now to explain what exactly I mean when I say our brains are set to a gender. First, it's important to realise the difference between gender and expression. Having a female gender doesn't mean that you love ponies, pink, housework and other stereotypically female things. Neither does having a male gender mean you enjoy drinking beer with your bros over a sports game every Sunday.
It simply means that your brain expects you to have certain sex characteristics. Gender dysphoria comes from when your brain finds your sex characteristics do not match your gender, and generally freaks out about it.
Note: I'm in no way, at all, an expert or even particularly well-informed about this stuff. This is really just dumbed-down speculation on my part.