I have to be understanding at this. Infamous, Prototype, and Dragon Age, while all sandbox and large games yes, don't have the involvement with the background and city as Fallout does. WoW doesn't count because it's been 10 years or something and they release patches to fix bugs since they have a huge team working on that 24/7 I'm sure
But FO has you interacting with almost everything. Each place you enter, whether or not it's meant for a quest, has stuff you can pick up. There's trash litered everywhere that people always just ignore, but it has to be there. Ruined books liter the houses also, and there's so much there, including certain places that I'm guessing have random amounts of objects in it (such as desks and such) that you really can't fault them for something breaking down when the entire field has to deal with this.
Now there are bugs that yes, they should have fixed, but there is only so much they can do. And honestly, I've learned from this to save at certain points and keep auto-save on, means I get lucky if I accidentally die, and if I have to restart I didn't lose all that progress, just save every once in awhile like we should.