Twilight Princess.
I got it at launch with high hopes, as I have played every single Zelda game before it, but the damn gimmicky "waggle waggle" combat controls just suck so completely hard, IMO. Shaking my wrist when I want a sword to swing just feels so clunky and imprecise, I just could never get into the game at all.
I'll buy it for Gamecube at some point, so I can at least play it for the story.