Okay, so this may have been said already; if it is, I'm simply adding my chip to the pile.
The layout, I've got no problems with, but some serious CSS work is needed, because the fonts look fugly. You know how fonts get at in-between sizes? When they're on the small side, entire strokes of letters disappear, making them illegible; when they're on the large side, random lines get thicker, and sometimes spiky. For a site that posts so many articles, making it difficult to read is shooting yourself in the foot.
Further examination implies you only tested your site in Internet Explorer, because it looks great in IE9. However, in Firefox 7.0.1 and Chrome 16.0.912.63, it looks awful. So please, do 40% or more of your readers a solid and work on your fonts.