I happened to be one of those who got to play Duke Nukem this year at PAX. I've never played the original games, (falling just on the cusp of "too young") but the game felt more like an homage to me than anything. Like it was paying tribute to the crude, over the top antics of nineties culture. You start the Goddamn game by taking a leak, (as in, "Press X to piss") and several of the guns have a max ammo capacity of 69. The game, or at least the demo, is self-aware, referencing its long development time and what-not. It certainly won't be anything we've never seen before, but it'll definitely be something we haven't seen in a very long time.